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Ibrexafungerp
Life-threatening Infections
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SCY-247
Ibrexafungerp
Life-threatening Infections
Invasive Fungal Infections
Invasive Candidiasis
Invasive Aspergillosis
MARIO
Community Infections
Vulvovaginal Candidiasis
Recurrent VVC
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Publications and Presentations
Our Science
Publications and Presentations
Date
Title
September 2018
Ibrexafungerp (formerly SCY-078) Displays Potent
In Vitro
Activity Against
C. glabrata
Isolates with Mutations in
fks
Genes
Stephen Barat, Katyna Borroto-Esoda, David Angulo
ESCMID ASM 2018
June 2018
SCY-078: A first-in-class, orally-bioavailable, glucan synthase inhibitor has broad spectrum activity against
Candida, Aspergillus
and
Pneumocystis
spp.
Stephen Barat, Katyna Borroto-Esoda, David Angulo
ISHAM 2018
June 2018
In vitro
Activity of SCY-078 in Combination with Isavuconazole or Amphotericin B against Medically Important Moulds
V. Petraitis, P. Kavaliauskas, R. Planciuniene, M.Viragailis, R.Petraitiene, S.Barat, K. Borroto-Esoada, D. Angulo, T. Walsh
ASM Microbe 2018
February 2018
Combination Therapy with SCY-078 and Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis
V. Petraitis, S. Barat, K. Borroto-Esoda, D. Angulo, T. Walsh
AAA 2018
October 2017
Assessment of the
In Vitro
Antifungal Activity of SCY-078 Against a Collection of
C. parapsilosis
Clinical Isolates
S. Barat, D. Angulo, K. Borroto-Esoda, M. Ghannoum
IDWeek 2017
October 2017
SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis
K. Borroto-Esoda, S. Barat, D. Angulo, C. Carruthers, K. Holden, P. Warn
IDWeek 2017
October 2017
SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration
S. Barat, K. Borroto-Esoda, D. Angulo, C. Carruthers
IDWeek 2017
August 2017
Vaginal Concentrations of SCY-078, a Novel Glucan Synthase Inhibitor, Following Oral Administration in Mice
S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo
IDSOG 2017
August 2017
The Effect of pH on the
In Vitro
Antifungal Activity of SCY-078
E. Larkin, C. Hager, L. Long, N. Isham, S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo, M. Ghannoum
IDSOG 2017
June 2017
In vitro
Interaction between SCY-078, Echinocandins and Azoles against Susceptible & Resistant
Candida
spp. Determined by the Checkerboard Method
K. Borroto-Esoda, B. Scorneaux, D. Angulo, S. Helou
ASM Microbe
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